Semaglutide titration schedule

The full Semaglutide titration ladder — 6 steps, what each one is for, the missed-dose window, and what the approved label says about holding.

Labelled product and use

Wegovy injection · once-weekly subcutaneous · adult weight-management path

Label source

Wegovy injection (weekly): US prescribing information, revised 06/2026. Primary source

Brand names

Wegovy, Ozempic, Rybelsus

Approval status

Approved since 2017 (Ozempic, type 2 diabetes), 2021 (Wegovy, weight management) and 2019 (Rybelsus, the oral tablet).

What this summary leaves out

The step amounts, timing and missed-dose rules come from the label itself, linked above; this summary does not reproduce them.

Educational use only, never medical advice. No doses.