Can I swap from one to another at the same dose?

Answer

There is no milligram-for-milligram equivalence between these compounds, and published conversion guidance warns specifically against jumping from a mid-range amount of one to the top of another.

In more detail

Health-system conversion guides exist and are built from head-to-head data on glycaemic and weight effect, but they carry two consistent caveats: the conversions do not address tolerability, and someone who had gut effects on one agent may need a step down when converting. Moving from a submaximal amount of one drug to the maximum of another is the specific pattern those guides warn about. Whether and how to switch is a prescribing decision.

Source

Published health-system GLP-1 receptor agonist conversion guidance (adapted from Whitley, Clinical Diabetes 2023).

Educational use only, never medical advice. No doses.