Can I drop to a lower dose once I hit my goal?

Answer

It is what most people want, and the trials cited here did not test whether a reduced maintenance amount holds the loss as well as continuing.

In more detail

The maintenance trials tested continuing at the amount that produced the loss, not stepping down from it. SURMOUNT-4 found that continuing tirzepatide preserved most of the loss. The question patients actually ask — whether 5 mg holds what 15 mg achieved — is not what those trials tested. Some prescribers lower the amount or lengthen the interval; the trials cited here do not evaluate that, and any change is a supervised one.

Source

SURMOUNT-4 (Aronne 2024, PMID 38078870); STEP 5 (Garvey 2022, PMID 36216945).

Educational use only, never medical advice. No doses.