Spermidine

Status

Dietary supplement (US). Sold as a dietary supplement. Not approved as a medicine.

What it is

A dietary polyamine studied for inducing autophagy, the cell's own recycling process.

What published research measured

A naturally occurring polyamine present in wheat germ, aged cheese and soy, and a well-established inducer of autophagy in cell and animal models where it extends lifespan across several species. Human evidence is mostly observational — dietary intake associated with lower mortality in cohort studies — plus small trials in cognition with mixed results. Association in a cohort is not an effect of a capsule.

Source

Not tied to a single designated source; see the published research on this molecule

Sources

No linked primary source is on file for this entry yet.

Educational use only, never medical advice. No doses.