P21

Also known as: P021

Status

No approved product. No FDA-approved labeling. Not an approved medicine in the United States, and no approval elsewhere is listed in this site's sources.

What it is

A small peptide derived from a fragment of CNTF, studied in animal models of neurogenesis.

What published research measured

Derived from a biologically active region of ciliary neurotrophic factor and modified for stability and brain penetration. Animal work in Alzheimer's models reported increased neurogenesis and reductions in tau pathology. No published human trial was identified. Everything said about it in the community is extrapolated from rodent studies, which for a compound acting on the brain is a longer leap than usual.

Source

Harper JW et al. 1993 — The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

Sources

No linked primary source is on file for this entry yet.

Educational use only, never medical advice. No doses.