Copper Tripeptide Serum
Status
Cosmetic ingredient. No FDA-approved drug labeling exists. GHK-Cu is regulated as a cosmetic ingredient in the United States and is not reviewed for therapeutic efficacy.
What it is
A blended skincare serum built around copper peptides.
What published research measured
Topically applied GHK-Cu, the copper complex of the glycyl-histidyl-lysine tripeptide. This is the best-evidenced peptide in the cosmetic category: controlled human studies of topical GHK-Cu report improvements in skin density, thickness, wrinkle depth and photodamage over twelve weeks, and its mechanisms — stimulating collagen and glycosaminoglycan synthesis, modulating metalloproteinases, and supporting wound repair — are well characterized in laboratory work. Two practical points recur in the literature. Copper peptides and direct vitamin C preparations are often advised apart because the low pH and reducing environment can destabilize the complex. And formulation matters more than concentration, since an unstable or poorly delivered preparation will not reproduce study conditions.
Source
Controlled topical studies of GHK-Cu on skin density and photodamage
Sources
No linked primary source is on file for this entry yet.
Educational use only, never medical advice. No doses.